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Interpol is an international police cooperation and law enforcement agency. They have a headquarters in France.
It at one point employed Chase Devineaux and Julia Argent. However, they were transferred to work for A.C.M.E.. A.C.M.E.'s Chief used to be an Interpol agent. Later on Mr. Devineaux was laid off A.C.M.E and sent back to Interpol. Then he was reactivated to capture Carmen Sandiego alongside Agent Argent.